Genotype-Frequency Estimation from High-Throughput Sequencing Data
نویسندگان
چکیده
منابع مشابه
Genotype-Frequency Estimation from High-Throughput Sequencing Data.
Rapidly improving high-throughput sequencing technologies provide unprecedented opportunities for carrying out population-genomic studies with various organisms. To take full advantage of these methods, it is essential to correctly estimate allele and genotype frequencies, and here we present a maximum-likelihood method that accomplishes these tasks. The proposed method fully accounts for uncer...
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ژورنال
عنوان ژورنال: Genetics
سال: 2015
ISSN: 1943-2631
DOI: 10.1534/genetics.115.179077